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Harry H.S. Fong, Ph.D. Harry Fong

Professor Emeritus of Pharmacognosy
Department of Medicinal Chemistry and Pharmacognosy

University of Illinois at Chicago
College of Pharmacy
833 S. Wood Street (M/C 781)
Chicago, IL 60612-7231

Office: 437 PHARM
Office Phone: 630-854-9303 (mobile)
Fax Number: 312-996-7107
E-mail address: hfong@uic.edu

Education:

The Ohio State University Ph.D. (Pharmacognosy) 1961-1965
University of Pittsburgh M.S. (Pharmacognosy) 1959-1961
University of Pittsburgh B.S. (Pharmacy) 1955-1959

Research Interests:

Bioassay-directed isolation, identification/structure elucidation of natural products anticancer, cancer chemoprevention, anti-malarial, anti-HIV, and anti-tuberculosis agents from higher planst; phytochemical analysis and standardization of medicinal plants and herbal products; monographing medicinal plants for the WHO Program on Traditional Medicine.

Professional Organizations:

American Society of Pharmacognosy
Society for Economic Botany

Edited Journals and Honorarium:

Journal of Natural Products (Associate Editor, 1993-1998)
WHO Monograph on Selected Medicinal Plants, Vol. 1-4  (Co-writer, 1997-present)

American Society of Pharmacognosy (Vice President 1977-1978; President 1978-1979; Society for Economic Botany (Treasurer, 1975-1977, Vice President 1980-1981, President 1981-1982), Honorary Visiting Research Fellow, Institute of Science and Technology, The Chinese University of Hong Kong (1977); Visiting Professor, Guangzhou University of Traditional Chinese Medicine, PRC; Visiting Professor,Universidad Nacional Mayor de San Marcos, Facultad de Medicina, Lima, Peru. Jack L. Beal Post Baccalaureate Alumnae Award, The Ohio State University 1997; Member of the WHO Expert Panel on Traditional Medicine (1997-2001; consultant to the WHO/TRM, WHO Regional Office for the Western Pacific, WHO Eastern Mediterranean Regional Office, WHO South East Regional Office; and the World Bank, Department of Population, Health and Nutrition. He is a member of the International Advisory Board on Hong Kong Regulatory Standards for Chinese Medicinal Herbs, Hong Kong, SAR, China (2001 - Present); a Member of the Strategic Advisory Panel, Hong Kong Jockey Club Institute of Chinese Medicine, Hong Kong, SAR, China (2002 - Present).Group

Selected Publications:

  1. Li W, Fong HHS, Singletary KW, Fitzloff JF. Determination of catechins in commercial gape seed extract. Journal of Liquid Chromatography & Related Technology, 2002, 25:397-407.
  2. Hoang, VD, Tan GT, Zhang H-J, Tamez PA, Hung NV, Cuong NM, Soejarto DD, Fong HHS, Pezzuto JM. Natural anti-HIV agents. Part I. (+)-demethoxyepiexcelsin and verticillatol from Litsea verticillata. Phytochmeistry  2002, 59:325-329.
  3.  Zhang H-J, Fan Z, Tan GT, Chai H-B, Pezzuto JM, Sun H, Fong HHS. Pseudoirroratin A, a new cytotoxic ent-kaurene diterpene from Isodon pseudo-irrorata. Journal of Natural Products, 2002, 65: 215-217.
  4.  Chen S-N, Li W, Fabricant DS, Santiarsiero BD, Mesecar A, Fitzloff JF, Fong HHS, Farnsworth NR. Isolation, structure elucidation and absolute configuration of 26-deoxyactein from Cimicifuga racemosa and clarification of nomenclature associated with 27-deoxyactein. Journal of Natural Products, 2002, 65:601-605
  5.  Hall T, Lu Z-Z, Yat PN, Fitzloff JF, Arnason JT, Awang DVC, Fong HHS, Blumenthal M. Evaluation of consistency of standardized Asian ginseng products in the ginseng evaluation program. HerbalGram, 2001, 52:31-45.
  6.  Liu J, Burdette JE, Xu H, Gu C, van Breemen RBv, Bhat, K, Booth N, Constantinou AI, Pezzuto JM, Fong HHS, Farnsworth NR, Bolton JL. Evaluation of estrogrnic activity of plant extracts for the potential treatment of menopausal symptoms. Journal of Agricultural  Food Chemistry, 2001, 49:2472-2479.
  7. Li S-H, Zhang H-J, Yao P, Sun H-D, Fong HHS. Taxane diterpenoids from the bark of Taxus yunanensis. Phytochemistry, 2001, 58:369-374.
  8. Sun H-D, Qiu S-X, Lobkovsky EB, Lin L-Z, Farnsworth NR, Clardy J, Fong HHS. Crystal and molecular structure of a natural equimolecular mixture of two epimeric diterpenes.  Tetrahedon, 2001,  57:65-70
  9. Li W-k, Gu C-g, Zhang H-j, Awang DVC, Fitzloff JF, Fong HHS, van Breemen RB. Use of high performance liquid chromatography-tandem  mass spectrometry to distinguish Panax ginseng C.A. Meyer (Asian ginseng) and Panax quinquefolius L. (North American ginseng).  Analytical  Chemistry , 2000, 72: 5417-5422.
  10. Chang LC, Chavez D, Gills JJ, Fong HHS, Pezzuto JM, Kinghorn AD. Rubiasins A-C, new anthracene derivatives from the roots and stems of Rubia cordifolia. Tetrahedron Letters , 2000, 41:7157-7162.
  11. Fong HHS, Kosmeder JW, Farnsworth NR, Soejarto DD, Kinghorn AD, J.M. Pezzuto. Edible plants as sources of cancer chemopreventive agents. Proc. Intern. Forum Trad. Med., Toyama, Oct. 16-17, 1999.
  12. Qiu S-x, Liu C,. Zhao S-x, Xia Z-c, Farnsworth NR,  Fong HHS. (1R,2S)-(-)-Mangochinine, a naturally-occurring dibenzopyrrocoline alkaloid from Manglietia chingii.  Tetrahedron Lett. 1998, 39:4167-4170.
  13. C. Peng, Bodenhausen G, Qiu S, Fong HHS, Farnsworth NR, Yuan S, Zheng C. Computer-assisted structure elucidation: Application of CISOC-SES to the resonance assignment and structure generation of betulinic acid. Mag. Res. Chem. 1998, 36:267-278 .
  14. Jiang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher, CWW,  Fong HHS, Farnsworth NR, Kinghorn AD, Mehta RG, Moon RC, Pezzuto JM. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science, 1997, 275, :218-220.
  15. Thompson LU, Seidl MM, Rickard SE, Orcheson LJ,  Fong HHS. Antitumorigenic effect of a mammalian lignan precursor from flaxseed. Nutr. Cancer ,1996, 26:159-165.
  16. van Breemen RB, Huang C-R, Lu Z-Z, Rimando A, Fong HHS, Fitzloff JF.  Electrospray liquid chromatography/mass spectrometry of ginsenosides. Anal. Chem. 1995, 67: 3985-3989 .
  17. Bunyapraphatsara N, Kasnick S, Elvin AT, Cordell GA, Fong HHS, Matlin SA, Hua Z-R, Roshdy S,. Kim HK, Rao PN, Zhou W-M, Long LB, Shen W-j, Liang H. Studies on the stability of (±)-gossypol,  (±)-gossypol acetic acid and (+)-gossypol. Thai J. Phytopharmacy . 1994, 1:1-9.
  18. Luyengi L, Che C-t, Bowen PE,Waller DP, Beecher CWW, Pezzuto JM, Fong HHS. Linusitamarin, a new phenylpropanoid glucoside from Linum usitatissimum  L., Journal of Natural Products.  1993, 56:2012-2015.
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